New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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‘Of course, that's about appropriate. I search for a Bodily idea of biological devices in a bottom-up way. I feel you could distinguish three traces of investigate in my group at this time. The very first worries chromosome composition: how do you get yourself a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've formulated visualisation techniques that enable us to review how, for example, SMC proteins loop DNA (video on Youtube) as a way to Create up chromosomes.
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, Groningen researchers present the outcome of their attempts to generate labs additional sustainable and supply tricks for other labs.
Regrettably, For some time immediately after Iijima’s report, the production of cleanse nanotubes was cumbersome. In 1996, nevertheless, the team of Richard Smalley at Rice College managed to supply one-walled carbon nanotubes at higher generate. Soon right after, I contacted Smalley, and we made a decision to join forces to measure the transportation through a single carbon nanotube.
2015, discovery that condensin is usually a hugely flexible protein composition; and 1st detection of DNA knots making use of nanopores
The coiled-coil with the human Rad50 DNA mend protein incorporates distinct segments of elevated adaptability
We condition micro organism into kinds that deviate from their organic phenotype. Especially, I will show our power to form Dwell E. coli germs into novel shapes which include rectangles, squares, triangles and circles.
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‘You shouldn't just think of the inquiries of tomorrow, but additionally think about the questions with the day following tomorrow’
Extremely amazing, but that wasn’t actually exactly where my fascination lay. I needed to pioneer And that i had the feeling that was no more possible, as the most intriguing elementary insights experienced currently been uncovered. But my subject experienced developed several enjoyable new tools ceesdekker.net to measure personal molecules. I made a decision which i needed to apply this to biology, to look at it from a Bodily viewpoint.’
In 1993 he was appointed as Associate Professor at Delft University of Technological know-how. Within the mid-nineties Dekker and his workforce accomplished accomplishment with the invention of the electronic Houses of carbon nanotubes, the main single-molecule transistor and also other nanoscience.
1999, 1st measurement in the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for a new Luttinger description of interacting electrons in nanotubes
2005, discovery of the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of extensive-selection conformational changes in Mre11/DNA mend complexes; and first power measurements with a DNA molecule inside a nanopore
At last, I'll briefly sketch some of our Suggestions to investigate the constructing of artificial cells, specially our initially ways to determine artificial mobile division.